MilliporeSigma™ anti-Tissue Plasminogen Activator Clone: GMA-043,

Catalog No.	Quantity	Conjugate
GF53100UG	100 μg	Unconjugated

Catalog No. GF53100UG Supplier MilliporeSigma™ Supplier No. GF53100UG

Description

Mouse Monoclonal Antibody

Specifically detects Tissue Plasminogen Activator Clone: GMA-043 in Human samples, and it is validated for ELISA, Immuno Blotting

Epidemiological studies have demonstrated that levels of plasma fibrinogen, von Willebrand factor (vWf), plasminogen activator inhibitor-1 (PAI-1) and tissue-type plasminogen activator (tPA) are associated with the incidence of vascular disease. Von Willebrand factor (vWF) is a large, multimeric glycoprotein mediating platelet adhesion at sites of endothelial damage. The process of acute release of tissue-type plasminogen activator (tPA) is important in locally speeding up fibrinolysis. Acutely released tPA and constitutively secreted tPA were liberated from different pathways in human umbilical vein endothelial cells. Plasma levels of tissue plasminogen activator to plasminogen activator/ inhibitor-1 complex, in addition to von Willebrand factor, are significant risk markers for recurrent myocardial infarction.

Specifications

• Antigen: Tissue Plasminogen Activator
• Applications: ELISA, Immunoblot, Immunoblot
• Classification: Monoclonal
• Clone: GMA-043
• Conjugate: Unconjugated
• Formulation: In 150mM NaCl, 10mM sodium phosphate, 1% mannitol, pH 7.4.
• Host Species: Mouse
• Immunogen: purified human tissue plasminogen activator (tPA)
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Test Specificity: Recognizes the ∽60kDa tPA protein.
• Target Species: Human
• Content And Storage: −20°C
• Form: Purified
• Isotype: IgG1

For Research Use Only