TMEM123, Rabbit, Monoclonal Antibody, Abnova™

Rabbit monoclonal antibody raised against a human TMEM123 peptide using ARM Technology.

Supplier:  Abnova Corporation H00114908K

Catalog No. 89-203-950

Includes: Up to three rabbit IgG clones of 1mg each will be delivered to customer.

Description

This gene encodes a highly glycosylated transmembrane protein with a high content of threonine and serine residues in its extracellular domain, similar to a broadly defined category of proteins termed mucins. Exposure of some cell types to anti-PORIMIN (pro-oncosis receptor inducing membrane injury) antibody, crosslinks this protein on the cell surface and induces a type of cell death termed oncosis. Oncosis is distinct from apoptosis and is characterized by a loss of cell membrane integrity without DNA fragmentation. This gene product is proposed to function as a cell surface receptor that mediates cell death. [provided by RefSeq

Library Construction: Nonfusion antibody library from rabbit spleen (ARM Technology)
Expression: Overexpression vector and transfection into 293H cell line

Order Info

1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.

Specifications

• Antigen: TMEM123
• Classification: Monoclonal
• Conjugate: Unconjugated
• Formulation: In 1X PBS, pH 7.4
• Gene Accession No.: TMEM123
• Gene Symbols: TMEM123
• Immunogen: A synthetic peptide of human TMEM123
• Regulatory Status: RUO
• Gene ID (Entrez): 114908
• Content And Storage: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
• Isotype: IgG

• Applications: ELISA, Western Blot
• Concentration: 1mg
• Description: transmembrane protein 123
• Gene: TMEM123
• Gene Alias: KCT3, PORIMIN, PORMIN
• Host Species: Rabbit
• Quantity: 1 mg x up to 3 Abs
• Primary or Secondary: Primary
• Target Species: Human
• Form: Liquid