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TNF Mouse anti-Human, PE, Clone: MAB11, BD

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Catalog No. BDB557068 Supplier BD Biosciences Supplier No. 557068
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Description

Mouse Monoclonal Antibody

Clone MAb11 reacts with the human form of tumor necrosis factor (TNF, formerly known as TNF-α) detectable in the cytoplasm of a major subset of activated peripheral blood T lymphocytes. Using standard procedures for detection of intracellular proteins, clone MAb11 also cross-reacts with activated peripheral blood CD3+ lymphocytes of baboon, and both rhesus and cynomolgus macaque monkeys following five-hour treatment with phorbol myristic acetate (PMA) and Ca++ Ionophore (A23187) in the presence of monensin. The staining is restricted to CD3+ T cells and is similar to that observed with peripheral blood T lymphocytes from normal human donors. This antibody is routinely tested by flow cytometric analysis. Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.

Host Species: Mouse
Clone: MAb11
Isotype: IgG1, κ
Species Reactivity: Human, Baboon/Rhesus/Cynomolgus
Immunogen: Recombinant Human TNF

Intracellular Staining

TRUSTED_SUSTAINABILITY

Specifications

Antigen TNF
Applications Flow Cytometry
Classification Monoclonal
Clone MAB11
Conjugate PE
Formulation Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Host Species Mouse
Immunogen Recombinant Human TNF
Purification Method Affinity Purified
Quantity 50 Tests
Regulatory Status RUO
Research Discipline Immunology
Primary or Secondary Primary
Target Species Baboon, Cynomolgus, Rhesus Monkey
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG1 κ
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For Research Use Only.

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