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TNF Mouse anti-Human, PE-Cy7, Clone: MAb11, BD

Catalog No. BDB560678 Shop All BD Biosciences Products
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BDB560678 50 Tests
BDB560923 25 Tests
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Catalog No. BDB560678 Supplier BD Biosciences Supplier No. 560678
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Description

Mouse Monoclonal Antibody

The MAb11 monoclonal antibody specifically binds to human tumor necrosis factor (TNF, also known as TNF- α ) protein. TNF is an efficient juxtacrine, paracrine and endocrine mediator of inflammatory and immune functions. It regulates the growth and differentiation of a variety of cell types. TNF is cytotoxic for transformed cells when in conjunction with IFN- γ. It is secreted by activated monocytes/macrophages and other cells such as B cells, T cells and fibroblasts. The immunogen used to generate the MAb11 hybridoma was recombinant human TNF. The MAb11 antibody has been reported to crossreact with Rhesus Macaque TNF.

TRUSTED_SUSTAINABILITY

Specifications

Antigen TNF
Applications Flow Cytometry
Classification Monoclonal
Clone MAb11
Conjugate PE-Cyanine7
Formulation Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Host Species Mouse
Immunogen Recombinant Human TNF
Purification Method Affinity Purified
Quantity 50 Tests
Regulatory Status RUO
Primary or Secondary Primary
Target Species Baboon, Cynomolgus, Rhesus Monkey
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG1 κ
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For Research Use Only.

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