tyrosine kinase, nonreceptor, 2, Mouse, Polyclonal Antibody, Abnova
Mouse polyclonal antibody raised against a partial recombinant TNK2.
Manufacturer: Abnova Corporation H00010188A01
This gene encodes a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain. The protein may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc42Hs and which is directly linked to a tyrosine phosphorylation signal transduction pathway. Several alternatively spliced transcript variants have been identified from this gene, but the full-length nature of only two transcript variants has been determined. [provided by RefSeqSequence: QYFLRLRDDLNVTRLSHFEYVKNEDLEKIGMGRPGQRRLWEAVKRRKALCKRKSWMSKVFSGKRLEAEFPPHHSQSTFRKTSPAPGGPAGEGPLQSLTCL
|tyrosine kinase, non-receptor, 2|
|ELISA, Western Blot|
|Mouse polyclonal antibody raised against a partial recombinant TNK2.|
|TNK2 (AAH08884, 21 a.a. ~ 120 a.a) partial recombinant protein with GST tag.|
|Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
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