MilliporeSigma™ anti-TNNI2, Polyclonal

Catalog No.	Quantity	Conjugate
CB1048100UG	100 μg	Unconjugated

Catalog No. CB1048100UG Supplier MilliporeSigma™ Supplier No. CB1048100UG

Description

Rabbit Polyclonal Antibody

Specifically detects TNNI2 Clone: in Human, Mouse samples, and it is validated for Immuno Blotting

This protein is a fast-twitch skeletal muscle protein, a member of the troponin I gene family, and a component of the troponin complex including troponin T, troponin C and troponin I subunits. The troponin complex, along with tropomyosin, is responsible for the calcium-dependent regulation of striated muscle contraction. Mouse studies show that this component is also present in vascular smooth muscle and may play a role in regulation of smooth muscle function. In addition to muscle tissues, this protein is found in corneal epithelium, cartilage where it is an inhibitor of angiogenesis to inhibit tumor growth and metastasis, and mammary gland where it functions as a co-activator of estrogen receptor-related receptor alpha. This protein also suppresses tumor growth in human ovarian carcinoma.

Specifications

• Antigen: TNNI2
• Applications: Immunoblot
• Classification: Polyclonal
• Conjugate: Unconjugated
• Formulation: In PBS, pH 7.2.
• Host Species: Rabbit
• Immunogen: Full-length, human TNNI2 (aa 1-182)
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Test Specificity: Recognizes the ∽25-27kDa TNNI2 protein in mouse spleen tissue.
• Target Species: Human, Mouse
• Content And Storage: −20°C
• Form: Purified
• Isotype: IgG

For Research Use Only