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TOM70 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA146188

Catalog No. PA146188


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Description

Description

Suggested positive control: purified mitochondrial extracts and HeLa whole cell extract.

Functional mitochondria require up to 1000 proteins to function properly, with 99% synthesized as precursors in the cytoplasm and transported into the mitochondria with the aid of cytosolic chaperones and mitochondrial translocators (import components). Proteins to be imported are chaperoned to the mitochondria by the cytosolic heat shock protein (cHSP70) and are immediately pursued by Translocators of the Outer Membrane (TOMs), followed by transient interactions of the unfolded proteins with Translocators of the Inner Membrane (TIMs). TOMM70A is ubiquitously expressed in human tissues and localizes in the mitochondria. TOMM70A could play a significant role in the import of nuclear-encoded mitochondrial proteins with internal targeting sites such as ADP/ATP carriers and the uncoupling proteins.
Specifications

Specifications

TOM70
Polyclonal
Unconjugated
TOMM70
Liquid
TOMM70, Tomm70a
Synthetic peptide made to a region within residues 1-100 of the human protein. [Swiss-ProtNo. O94826].
Protein A
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Immunocytochemistry, Immunofluorescence, Western Blot
1 mg/mL
PBS with no preservative
O94826, Q9CZW5, Q75Q39
FLJ90470
Rabbit
IgG
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
28185, 304017, 9868
Documents
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