TPO, Mouse, Clone: 6H7, Abnova™

Mouse monoclonal antibody raised against TPO.

Supplier:  Abnova Corporation MAB8344

Catalog No. 89-024-827

Description

This gene encodes a membrane-bound glycoprotein. The encoded protein acts as an enzyme and plays a central role in thyroid gland function. The protein functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mutations in this gene are associated with several disorders of thyroid hormonogenesis, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA. Multiple transcript variants encoding distinct isoforms have been identified for this gene. Additional splice variants have been described but their biological natures have not been determined. [provided by RefSeq

Specifications

• Antigen: TPO
• Classification: Monoclonal
• Conjugate: Unconjugated
• Dilution: The optimal working dilution should be determined by the end user.
• Gene: TPO
• Gene Symbols: TPO
• Immunogen: Purified human TPO.
• Regulatory Status: RUO
• Gene ID (Entrez): 7173
• Target Species: Human
• Form: Liquid

• Applications: ELISA
• Clone: 6H7
• Description: Mouse monoclonal antibody raised against TPO.
• Formulation: In PBS, pH 7.4 (0.09% sodium azide)
• Gene Alias: MSA/TPX
• Host Species: Mouse
• Quantity: 100 μg
• Primary or Secondary: Primary
• Test Specificity: These antibodies react specifically with human thyroid peroxidase.
• Content And Storage: Store at -20°C. For long term storage store at -80°C.
  Aliquot to avoid repeated freezing and thawing.
• Isotype: IgG1