TPO, Mouse, Clone: 6H7, Abnova™

Catalog No.	Quantity
89-024-827	100 μg

Catalog No. 89-024-827 Supplier Abnova Corporation Supplier No. MAB8344

Description

Mouse monoclonal antibody raised against TPO.

This gene encodes a membrane-bound glycoprotein. The encoded protein acts as an enzyme and plays a central role in thyroid gland function. The protein functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mutations in this gene are associated with several disorders of thyroid hormonogenesis, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA. Multiple transcript variants encoding distinct isoforms have been identified for this gene. Additional splice variants have been described but their biological natures have not been determined. [provided by RefSeq

Specifications

• Antigen: TPO
• Applications: ELISA
• Classification: Monoclonal
• Clone: 6H7
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against TPO.
• Dilution: The optimal working dilution should be determined by the end user.
• Formulation: In PBS, pH 7.4 (0.09% sodium azide)
• Gene: TPO
• Gene Alias: MSA/TPX
• Gene Symbols: TPO
• Host Species: Mouse
• Immunogen: Purified human TPO.
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 7173
• Test Specificity: These antibodies react specifically with human thyroid peroxidase.
• Target Species: Human
• Content And Storage: Store at -20°C. For long term storage store at -80°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid
• Isotype: IgG1