TRA-1-60 Mouse anti-Human, Alexa Fluor 647, Clone: TRA-1-60, BD

Catalog No.	Quantity
BDB560122	100 Tests

Catalog No. BDB560122 Supplier BD Biosciences Supplier No. 560122

Description

Mouse Monoclonal Antibody

The TRA-1-60 monoclonal antibody reacts with a pluripotent-stem-cell-specific epitope on a high-molecular-weight transmembrane glycoprotein. The TRA-1-60 antigen is a sialylated epitope on the same keratan sulfate core molecule, podocalyxin, as 4 other distinct antigens on tumor-derived cell lines, TRA-1-81, GCTM2, K4, and K21. The expression of TRA-1-60 antigen is stage-specific and can be used to characterize embryonic cells and monitor their differentiation. The antigen is found on teratocarcinoma (embryonal carcinoma or EC), embryonic inner cell mass (but not morula or trophoblast), and embryonic stem (ES) cells. TRA-1-60 antigen is released into the serum of patients bearing testicular tumors containing EC cells. As human EC and ES cells undergo differentiation, expression of TRA-1-60 antigen is lost. This antibody is routinely tested by immunofluorescence imaging. Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.

Host Species: Mouse
Clone: TRA-1-60
Isotype: IgM, κ
Species Reactivity: Human
Immunogen: Human Embryonal Carcinoma Cell Line

Bioimaging

Specifications

• Antigen: TRA-1-60
• Applications: In vitro Assay
• Classification: Monoclonal
• Clone: TRA-1-60
• Conjugate: Alexa Fluor 647
• Description: TRA-1-60(R)
• Formulation: Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.
• Host Species: Mouse
• Immunogen: Human Embryonal Carcinoma Cell Line
• Purification Method: Affinity Purified
• Quantity: 100 Tests
• Regulatory Status: RUO
• Research Discipline: Cell Biology
• Primary or Secondary: Primary
• Target Species: Human, Rhesus Monkey
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
• Isotype: IgM κ