TRA-1-81 Mouse anti-Human, Alexa Fluor 555, Clone: TRA-1-81, BD

Mouse Monoclonal Antibody

Supplier:  BD Biosciences 560123

Catalog No. BDB560123

Description

The TRA-1-81 monoclonal antibody reacts with a pluripotent-stem-cell-specific epitope on a high-molecular-weight transmembrane glycoprotein. The TRA-1-81 antigen is an epitope on the same keratan sulfate core molecule, podocalyxin, as 4 other distinct antigens on tumor-derived cell lines, TRA-1-60, GCTM2, K4, and K21. The expression of TRA-1-81 antigen is stage-specific and can be used to characterize embryonic cells and monitor their differentiation. The antigen is found on teratocarcinoma (embryonal carcinoma or EC), embryonic inner cell mass (but not morula or trophoblast), and embryonic stem (ES) cells. As human EC and ES cells undergo differentiation, expression of TRA-1-81 antigen is lost. This antibody is routinely tested by immunofluorescent imaging. Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.

Host Species: Mouse
Clone: TRA-1-81
Isotype: IgM, κ
Species Reactivity: Human
Immunogen: Human Embryonal Carcinoma Cell Line

Bioimaging

Specifications

• Antigen: TRA-1-81
• Classification: Monoclonal
• Conjugate: Alexa Fluor 555
• Host Species: Mouse
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

• Applications: In vitro Assay
• Clone: TRA-1-81
• Formulation: Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.
• Immunogen: Human Embryonal Carcinoma Cell Line
• Quantity: 100 Tests
• Research Discipline: Cell Biology
• Target Species: Human, Rhesus Monkey
• Isotype: IgM κ