TRAF3 interacting protein 2, Mouse, Clone: 4A3, Abnova™

Catalog No.	Quantity
89-014-268	100 μg

Catalog No. 89-014-268 Supplier Abnova Corporation Supplier No. H00010758M01

Description

Mouse monoclonal antibody raised against a partial recombinant TRAF3IP2.

This gene encodes a protein involved in regulating responses to cytokines by members of the Rel/NF-kappaB transcription factor family. These factors play a central role in innate immunity in response to pathogens, inflammatory signals and stress. This gene product interacts with TRAF proteins (tumor necrosis factor receptor-associated factors) and either I-kappaB kinase or MAP kinase to activate either NF-kappaB or Jun kinase. Several alternative transcripts encoding different isoforms have been identified. Another transcript, which does not encode a protein and is transcribed in the opposite orientation, has been identified. Overexpression of this transcript has been shown to reduce expression of at least one of the protein encoding transcripts, suggesting it has a regulatory role in the expression of this gene. [provided by RefSeq

Sequence: LRDKTVMIIVAISPKYKQDVEGAESQLDEDEHGLHTKYIHRMMQIEFIKQGSMNFRFIPVLFPNAKKEHVPTWLQNTHVYSWPKNKKNILLRLLREEEYVAPPRGPLPTLQVVPL

Specifications

• Antigen: TRAF3 interacting protein 2
• Applications: ELISA, Immunofluorescence, Immunohistochemistry (PFA fixed), Western Blot
• Classification: Monoclonal
• Clone: 4A3
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against a partial recombinant TRAF3IP2.
• Formulation: PBS with no preservative; pH 7.4
• Gene: TRAF3IP2
• Gene Accession No.: BC002823
• Gene Alias: ACT1/C6orf2/C6orf4/C6orf5/C6orf6/CIKS/DKFZp586G0522/MGC3581
• Gene Symbols: TRAF3IP2
• Host Species: Mouse
• Immunogen: TRAF3IP2 (AAH02823, 451 a.a. ∼ 565 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
• Purification Method: Affinity Purified
• Quantity: 100 μg
• Regulatory Status: RUO
• Research Discipline: Signal Transduction
• Primary or Secondary: Primary
• Gene ID (Entrez): 10758
• Target Species: Human
• Content And Storage: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
• Product Type: Antibody
• Isotype: IgG2a κ