KCNK18 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA520873
A suggested positive control is rat brain tissue lysate. PA5-20873 can be used with blocking peptide PEP-0987.TRESK (TWIK-related spinal cord K+ channel) is a two-pore domain K+ channel that induces outward rectification and functions as a background K+ channel that is abundantly expressed in the spinal cord, thymus, spleen, and leukemic T-lymphocytes. TRESK is activated by increased cytoplasmic calcium concentration through calcineurin as well as by acetylcholine and histamine. It has been suggested that TRESK is linked to acute and chronic pain by activation of calcineurin. Other studies indicate that TRESK may play a role in the regulation of T-cell function and could be an excellent target to treat T-cell originated immune dysfunction.
|A 17 amino acid peptide from near the center of human TRESK.|
|Antigen affinity chromatography|
|Human, Mouse, Rat|
|Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot|
|PBS with 0.02% sodium azide|
|Q7Z418, Q6VV64, Q6Q1P3|
|K2p18.1, MGR13, TRESK, TRESK-2, TRESK2, TRIK; TWIK-related individual K+ channel; TWIK-related individual potassium channel; TWIK-related spinal cord K+ channel; TWIK-related spinal cord potassium channel; potassium channel subfamily K member 18|
|Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C|
|332396, 338567, 445371|
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