three prime repair exonuclease 1, Mouse, Purified MaxPab™ Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-017-023	50 μg

Catalog No. 89-017-023 Supplier Abnova Corporation Supplier No. H00011277B01P

Description

Mouse polyclonal antibody raised against a full-length human TREX1 protein.

This gene encodes the major 3'->5' DNA exonuclease in human cells. The protein is a nonprocessive exonuclease that may serve a proofreading function for a human DNA polymerase. It is also a component of the SET complex, and acts to rapidly degrade 3' ends of nicked DNA during granzyme A-mediated cell death. Mutations in this gene result in Aicardi-Goutieres syndrome, chilblain lupus, and Cree encephalitis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Sequence: MQTLIFFDMEATGLPFSQPKVTELCLLAVHRCALESPPTSQGPPPTVPPPPRVVDKLSLCVAPGKACSPAASEITGLSTAVLAAHGRQCFDDNLANLLLAFLRRQPQPWCLVAHNGDRYDFPLLQAELAMLGLTSALDGAFCVDSITALKALERASSPSEHGPRKSYSLGSIYTRLYGQSPPDSHTAEGDVLALLSICQWRPQALLRWVDAHARPFGTIRPMYGVTASARTKPRPSAVTTTAHLATTRNTSPSLRESRGTKDLPPVKDPGALSREGLLAPLGLLAILTLAVATLYGLSLATPGE

Specifications

• Antigen: three prime repair exonuclease 1
• Applications: Western Blot
• Classification: Polyclonal
• Conjugate: Unconjugated
• Description: Mouse polyclonal antibody raised against a full-length human TREX1 protein.
• Formulation: PBS with no preservative; pH 7.4
• Gene: TREX1
• Gene Accession No.: NM_007248
• Gene Alias: AGS1/AGS5/CRV/DKFZp434J0310/DRN3/HERNS
• Gene Symbols: TREX1
• Host Species: Mouse
• Immunogen: TREX1 (NP_009179, 1 a.a. ∼ 304 a.a) full-length human protein.
• Purification Method: Affinity Purified
• Quantity: 50 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 11277
• Target Species: Human
• Content And Storage: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
• Product Type: Antibody
• Isotype: IgG