three prime repair exonuclease 1, Mouse, Purified MaxPab™ Polyclonal Antibody, Abnova™

Mouse polyclonal antibody raised against a full-length human TREX1 protein.

Manufacturer: Abnova Corporation H00011277B01P

Catalog No. 89-017-023

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    Specifications

    Formulation In 1X PBS, pH 7.4
    Gene TREX1
    Gene Accession No. NM_007248
    Gene Alias AGS1, AGS5, CRV, DKFZp434J0310, DRN3, HERNS
    Gene Symbols TREX1
    Applications Western Blotting
    Species Reactivity Human
    Storage Requirements Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
    Gene ID (Entrez) 11277
    Description three prime repair exonuclease 1
    Antigen three prime repair exonuclease 1
    Quantity 50μg
    Format Affinity Purified
    Host Species Mouse
    Immunogen TREX1 (NP_009179, 1 a.a. ∽304 a.a) full-length human protein.
    Purification Method Protein A column
    Regulatory Status RUO
    Primary or Secondary Primary
    Monoclonal or Polyclonal Polyclonal
    Conjugate Unlabeled
    Cross Reactivity Human

    This gene encodes the major 3'->5' DNA exonuclease in human cells. The protein is a nonprocessive exonuclease that may serve a proofreading function for a human DNA polymerase. It is also a component of the SET complex, and acts to rapidly degrade 3' ends of nicked DNA during granzyme A-mediated cell death. Mutations in this gene result in Aicardi-Goutieres syndrome, chilblain lupus, and Cree encephalitis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq

    Sequence: MQTLIFFDMEATGLPFSQPKVTELCLLAVHRCALESPPTSQGPPPTVPPPPRVVDKLSLCVAPGKACSPAASEITGLSTAVLAAHGRQCFDDNLANLLLAFLRRQPQPWCLVAHNGDRYDFPLLQAELAMLGLTSALDGAFCVDSITALKALERASSPSEHGPRKSYSLGSIYTRLYGQSPPDSHTAEGDVLALLSICQWRPQALLRWVDAHARPFGTIRPMYGVTASARTKPRPSAVTTTAHLATTRNTSPSLRESRGTKDLPPVKDPGALSREGLLAPLGLLAILTLAVATLYGLSLATPGE

  • Description & Specifications

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