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TREX1, Rabbit, Monoclonal Antibody, Abnova™

Catalog No. 89201078 Shop All Abnova Corporation Products
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1 mg x up to 3 Abs
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Catalog No. Quantity
89-201-078 1 mg x up to 3 Abs
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Catalog No. 89-201-078 Supplier Abnova Corporation Supplier No. H00011277K

Description

Includes

Up to three rabbit IgG clones of 1mg each will be delivered to customer.

Rabbit monoclonal antibody raised against a human TREX1 peptide using ARM Technology.

This gene encodes the major 3'->5' DNA exonuclease in human cells. The protein is a nonprocessive exonuclease that may serve a proofreading function for a human DNA polymerase. It is also a component of the SET complex, and acts to rapidly degrade 3' ends of nicked DNA during granzyme A-mediated cell death. Mutations in this gene result in Aicardi-Goutieres syndrome, chilblain lupus, and Cree encephalitis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Library Construction: Nonfusion antibody library from rabbit spleen (ARM Technology)
Expression: Overexpression vector and transfection into 293H cell line

Order Info

  1. Customer may provide cell or tissue lysate for antibody screening.
  2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.

Specifications

Antigen TREX1
Applications ELISA, Western Blot
Classification Monoclonal
Concentration 1mg
Conjugate Unconjugated
Description three prime repair exonuclease 1
Formulation In 1X PBS, pH 7.4
Gene TREX1
Gene Accession No. TREX1
Gene Alias AGS1, AGS5, CRV, DKFZp434J0310, DRN3, HERNS
Gene Symbols TREX1
Host Species Rabbit
Immunogen A synthetic peptide of human TREX1
Quantity 1 mg x up to 3 Abs
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11277
Target Species Human
Content And Storage Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Form Liquid
Isotype IgG
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