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Description
This gene encodes a member of the tripartite motif (TRIM) family, whose members are involved in diverse cellular functions such as developmental patterning and oncogenesis. The TRIM motif includes zinc-binding domains, a RING finger region, a B-box motif and a coiled-coil domain. The RING finger and B-box domains chelate zinc and might be involved in protein-protein and/or protein-nucleic acid interactions. The gene mutations are associated with mulibrey (muscle-liver-brain-eye) nanism, an autosomal recessive disorder that involves several tissues of mesodermal origin. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq
Specifications
Specifications
| Antigen | tripartite motif-containing 37 |
| Applications | ELISA, Western Blot |
| Classification | Monoclonal |
| Clone | 2D11 |
| Conjugate | Unconjugated |
| Description | Mouse monoclonal antibody raised against a partial recombinant TRIM37. |
| Formulation | PBS with no preservative; pH 7.4 |
| Gene | TRIM37 |
| Gene Accession No. | NM_015294 |
| Gene Alias | KIAA0898/MUL/POB1/TEF3 |
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