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TROP-2 Mouse anti-Human, Brilliant Violet 421, Clone: 162-46, BD

Catalog No. BDB563243 Shop All BD Biosciences Products
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BDB563243 50 μg
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Catalog No. BDB563243 Supplier BD Biosciences Supplier No. 563243
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Description

Mouse Monoclonal Antibody

The 162-46 monoclonal antibody recognizes human Trop-2 which is also known as GA733-1. Trop-2 is encoded by TACSTD2 (tumor-associated calcium signal transducer 2). It is a single-pass type-1 transmembrane glycoprotein. Trop-2 was originally identified to be expressed on human trophoblast and choriocarcinoma cell lines. Trop-2 is expressed in most human carcinomas. Trop-2 appears to be involved in the transduction of an intracellular calcium signal, although the exact physiological mechanism has yet to be elucidated.

TRUSTED_SUSTAINABILITY

Specifications

Antigen TROP-2
Applications Flow Cytometry
Classification Monoclonal
Clone 162-46
Concentration 0.2mg/mL
Conjugate Brilliant Violet 421
Description GA733-1; TROP2; EGP-1; EGP1; GP50; M1S1; TACD2
Formulation Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Host Species Mouse
Immunogen Human BeWo (choriocarcinoma) Cell Line
Purification Method Affinity Purified
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG1 κ
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