TROP-2 Mouse anti-Human, Unlabeled, Clone: 162-46, BD

Mouse Monoclonal Antibody

Supplier:  BD Biosciences 551317

Catalog No. BDB551317

Description

Trop-2/GA733-1 is a cell surface glycoprotein that was originally identified on human trophoblast and choriocarcinoma cell lines and has been shown to be expressed in most human carcinomas. Trop-2 has been cloned and shown to encode a type-1 transmembrane protein with a single transmembrane domain. Furthermore, research has shown Trop-2 to be involved in the transduction of an intracellular calcium signal, although the exact physiological mechanism has yet to be elucidated. The antibody recognizes human Trop-2. Cells from the human choriocarcinoma cell line BeWo were used as the immunogen.

Host Species: Mouse
Clone: 162-46
Isotype: IgG1 κ
Species Reactivity: Human
Immunogen: Human choriocarcinoma cell line BeWo

Flow Cytometry

Specifications

• Antigen: TROP-2
• Classification: Monoclonal
• Concentration: 0.5mg/mL
• Description: GA733-1; TROP2; EGP-1; EGP1; GP50; M1S1; TACD2
• Host Species: Mouse
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C

• Applications: Flow Cytometry
• Clone: 162-46
• Conjugate: Unconjugated
• Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
• Immunogen: Human choriocarcinoma cell line BeWo
• Quantity: 100 μg
• Research Discipline: Cell Biology
• Target Species: Human
• Isotype: IgG1 κ

For Research Use Only.