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Description
This gene encodes a DNA-binding protein which specifically recognizes conserved target sequences at the breakpoint junction of chromosomal translocations. Translin polypeptides form a multimeric structure that is responsible for its DNA-binding activity. Recombination-associated motifs and translin-binding sites are present at recombination hotspots and may serve as indicators of breakpoints in genes which are fused by translocations. These binding activities may play a crucial role in chromosomal translocation in lymphoid neoplasms. [provided by RefSeq
Specifications
Specifications
| Antigen | translin |
| Applications | ELISA, Western Blot |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Description | Mouse polyclonal antibody raised against a partial recombinant TSN. |
| Formulation | 50% glycerol |
| Gene | TSN |
| Gene Accession No. | NM_004622 |
| Gene Alias | BCLF-1/REHF-1/TRSLN |
| Gene Symbols | TSN |
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