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Tyrosine Hydroxylase Mouse anti-Rat, Unlabeled, Clone: TOH A1, BD

Catalog No. BDB556311 Shop All BD Biosciences Products
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BDB556311 0.1 mg
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Catalog No. BDB556311 Supplier BD Biosciences Supplier No. 556311

Description

Mouse Monoclonal Antibody

The catecholamine neurotranmitters, dopamine, noradrenaline and adrenaline, are involved in multiple physiological processes and neurological disorders. These three transmitters are synthesized from the amino acid tyrosine in a common pathway that uses five enzymes: tyrosine hydroxylase, aromatic amino acid decarboxylase, dopamine β hydroxylase, pteridine reductase, and phenylethanolamine-N-methyl transferase. Tyrosine hydroxylase, is the rate-limiting enzyme in catecholamine synthesis. It converts tyrosine to L-dihydroxyphenylalanine (L-DOPA), which is then further converted to give rise to dopamine, noradrenaline and adrenaline. Antibodies against these biosynthetic enzymes have been widely used in the immunohistochemical analysis of catecholaminergic neurons. TOH A1 specifically reacts with rat tyrosine hydroxylase and can be used to identify tyrosine hydroxylase containing catecholaminergic neurons in rat brain.

Host Species: Mouse
Clone: TOH A1
Isotype: IgG1
Species Reactivity: Rat
Immunogen: Tyrosine hydroxylase purified from the PC12 rat pheochromocytoma cell line

Electron Microscopy, Immunohistochemistry (Frozen)

TRUSTED_SUSTAINABILITY

Specifications

Antigen Tyrosine Hydroxylase
Applications Immunohistochemistry (Frozen)
Classification Monoclonal
Clone TOH A1
Concentration 0.5mg/mL
Conjugate Unconjugated
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species Mouse
Immunogen Tyrosine hydroxylase purified from the PC12 rat pheochromocytoma cell line
Purification Method Affinity Purified
Quantity 0.1 mg
Regulatory Status RUO
Research Discipline Cell Biology
Primary or Secondary Primary
Target Species Rat
Content And Storage Store undiluted at 4°C
Isotype IgG1
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For Research Use Only.

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