UAP56 Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA527427
PA5-27427 targets UAP56 in IF, IHC (P), and WB applications and shows reactivity with Human samples. The PA5-27427 immunogen is recombit fragment corresponding to a region within amino acids 1 and 304 of Human UAP56. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.This gene encodes a member of the DEAD box family of RNA-dependent ATPases that mediate ATP hydrolysis during pre-mRNA splicing. The encoded protein is an essential splicing factor required for association of U2 small nuclear ribonucleoprotein with pre-mRNA, and also plays an important role in mRNA export from the nucleus to the cytoplasm. A cluster of genes, BAT1-BAT5, is localized in the vicinity of the genes for TNF alpha and TNF beta. These genes are all within the human major histocompatibility complex class III region. Mutations in this gene may be associated with rheumatoid arthritis. Alternatively spliced transcript variants encoding the same protein have been described.
|Recombit fragment corresponding to a region within amino acids 1 and 304 of Human UAP56|
|Antigen affinity chromatography|
|Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot|
|0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7|
|BAT1, D6S81E, UAP56, 56 kDa U2AF65-associated protein, ATP-dependent RNA helicase p47, HLA-B-associated transcript 1 protein, nuclear RNA helicase (DEAD family), spliceosome RNA helicase BAT1, spliceosome RNA helicase DDX39B|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
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