UBE2D1, Rabbit, Monoclonal Antibody, Abnova™

Rabbit monoclonal antibody raised against a human UBE2D1 peptide using ARM Technology.

Supplier:  Abnova Corporation H00007321K

Catalog No. 89-203-428

Includes: Up to three rabbit IgG clones of 1mg each will be delivered to customer.

Description

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is closely related to a stimulator of iron transport (SFT), and is up-regulated in hereditary hemochromatosis. It also functions in the ubiquitination of the tumor-suppressor protein p53 and the hypoxia-inducible transcription factor HIF1alpha by interacting with the E1 ubiquitin-activating enzyme and the E3 ubiquitin-protein ligases. [provided by RefSeq

Library Construction: Nonfusion antibody library from rabbit spleen (ARM Technology)
Expression: Overexpression vector and transfection into 293H cell line

Order Info

1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.

Specifications

• Antigen: UBE2D1
• Classification: Monoclonal
• Conjugate: Unconjugated
• Formulation: In 1X PBS, pH 7.4
• Gene Accession No.: UBE2D1
• Gene Symbols: UBE2D1
• Immunogen: A synthetic peptide of human UBE2D1
• Regulatory Status: RUO
• Gene ID (Entrez): 7321
• Content And Storage: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
• Isotype: IgG

• Applications: ELISA, Western Blot
• Concentration: 1mg
• Description: ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast)
• Gene: UBE2D1
• Gene Alias: E2(17)KB1, SFT, UBC4/5, UBCH5, UBCH5A
• Host Species: Rabbit
• Quantity: 1 mg x up to 3 Abs
• Primary or Secondary: Primary
• Target Species: Human
• Form: Liquid