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Description
The protein encoded by this gene belongs to the ubiquitin-conjugating enzyme family. This protein interacts with RING finger proteins, and it can ubiquitinate huntingtin, the gene product for Huntington's disease. Known functions for this protein include a role in aggregate formation of expanded polyglutamine proteins and the suppression of apoptosis in polyglutamine diseases, a role in the dislocation of newly synthesized MHC class I heavy chains from the endoplasmic reticulum, and involvement in foam cell formation. Multiple transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq]
Specifications
Specifications
| Antigen | UBE2K |
| Applications | ELISA, Western Blot |
| Classification | Monoclonal |
| Clone | 1D10 |
| Conjugate | Unconjugated |
| Description | Mouse monoclonal antibody raised against a full-length recombinant UBE2K. |
| Formulation | PBS with no preservative; pH 7.4 |
| Gene | UBE2K |
| Gene Accession No. | BC006419 |
| Gene Alias | DKFZp564C1216/DKFZp686J24237/E2-25K/HIP2/HYPG/LIG |
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