ubiquitin protein ligase E3 component n-recognin 1, Mouse, Polyclonal Antibody, Abnova
Mouse polyclonal antibody raised against a partial recombinant UBR1.
Manufacturer: Abnova Corporation H00197131A01
The N-end rule pathway is one proteolytic pathway of the ubiquitin system. The recognition component of this pathway, encoded by this gene, binds to a destabilizing N-terminal residue of a substrate protein and participates in the formation of a substrate-linked multiubiquitin chain. This leads to the eventual degradation of the substrate protein. The protein described in this record has a RING-type zinc finger and a UBR-type zinc finger. Mutations in this gene have been associated with Johanson-Blizzard syndrome. [provided by RefSeqSequence: ADEEAGGTERMEISAELPQTPQRLASWWDQQVDFYTAFLHHLAQLVPEIYFAEMDPDLEKQEESVQMSIFTPLEWYLFGEDPDICLEKLKHSGAFQLCG
|ubiquitin protein ligase E3 component n-recognin 1|
|ELISA, Western Blot|
|Mouse polyclonal antibody raised against a partial recombinant UBR1.|
|UBR1 (NP_777576, 2 a.a. ~ 100 a.a) partial recombinant protein with GST tag.|
|Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
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