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ubiquitin protein ligase E3 component n-recognin 1, Mouse, Polyclonal Antibody, Abnova™

Mouse polyclonal antibody raised against a partial recombinant UBR1.

Supplier:  Abnova Corporation H00197131A01

Catalog No. 89-004-813


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Description

Description

The N-end rule pathway is one proteolytic pathway of the ubiquitin system. The recognition component of this pathway, encoded by this gene, binds to a destabilizing N-terminal residue of a substrate protein and participates in the formation of a substrate-linked multiubiquitin chain. This leads to the eventual degradation of the substrate protein. The protein described in this record has a RING-type zinc finger and a UBR-type zinc finger. Mutations in this gene have been associated with Johanson-Blizzard syndrome. [provided by RefSeq

Sequence: ADEEAGGTERMEISAELPQTPQRLASWWDQQVDFYTAFLHHLAQLVPEIYFAEMDPDLEKQEESVQMSIFTPLEWYLFGEDPDICLEKLKHSGAFQLCG
Specifications

Specifications

ubiquitin protein ligase E3 component n-recognin 1
Polyclonal
Mouse polyclonal antibody raised against a partial recombinant UBR1.
UBR1
JBS/MGC142065/MGC142067
Mouse
50 μL
Ubiquitin/Proteasome
Primary
Human
Serum
ELISA, Western Blot
Unconjugated
50% glycerol
NM_17491
UBR1
UBR1 (NP_777576, 2 a.a. ∼ 100 a.a) partial recombinant protein with GST tag.
RUO
Yes
197131
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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