uncoupling protein 2 (mitochondrial, proton carrier), Mouse, Purified MaxPab™ Polyclonal Antibody, Abnova™

Mouse polyclonal antibody raised against a full-length human UCP2 protein.

Manufacturer: Abnova Corporation H00007351B01P

Catalog No. 89-016-926

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    Specifications

    Antigen uncoupling protein 2 (mitochondrial, proton carrier)
    Applications Western Blotting
    Conjugate Unlabeled
    Cross Reactivity Human,Rat
    Description uncoupling protein 2 (mitochondrial, proton carrier)
    Format Affinity Purified
    Formulation In 1X PBS, pH 7.4
    Gene UCP2
    Gene Accession No. BC011737
    Gene Alias BMIQ4, SLC25A8, UCPH
    Gene Symbols UCP2
    Host Species Mouse
    Immunogen UCP2 (AAH11737, 1 a.a. ∽310 a.a) full-length human protein.
    Purification Method Protein A column
    Quantity 50μg
    Regulatory Status RUO
    Species Reactivity Human, Rat
    Storage Requirements Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
    Primary or Secondary Primary
    Monoclonal or Polyclonal Polyclonal
    Gene ID (Entrez) 7351

    Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. UCPs contain the three homologous protein domains of MACPs. This gene is expressed in many tissues, with the greatest expression in skeletal muscle. It is thought to play a role in nonshivering thermogenesis, obesity and diabetes. Chromosomal order is 5'-UCP3-UCP2-3'. [provided by RefSeq

    Sequence: MVGFKATDVPPTATVKFLGAGTAACIADLITFPLGTAKVRLQIQGESQGPVRATASAQYRGVMGTILTMVRTEGPRSLYNGLVAGLQRQMSFASVRIGLYDSVKQFYTKGSEHASIGSRLLAGSTTGALAVAVAQPTDVVKVRFQAQARAGGGRRYQSTVNAYKTIAREEGFRGLWKGTSPNVARNAIVNCAELVTYDLIKDALLKANLMTDDLPCHFTSAFGAGFCTTVIASPVDVVKTRYMNSALGQYSSAGHCALTMLQKEGPRAFYKGFMPSFLRLGSWNVVMFVTYEQLKRALMAACTSREAPF

  • Description & Specifications

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