UGT1A6, Rabbit, Monoclonal Antibody, Abnova™

Rabbit monoclonal antibody raised against a human UGT1A6 peptide using ARM Technology.

Supplier:  Abnova Corporation H00054578K

Catalog No. 89-200-527

Includes: Up to three rabbit IgG clones of 1mg each will be delivered to customer.

Description

This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The enzyme encoded by this gene is active on phenolic and planar compounds. Alternative splicing in the unique 5' end of this gene results in two transcript variants. [provided by RefSeq]

Library Construction: Nonfusion antibody library from rabbit spleen (ARM Technology)
Expression: Overexpression vector and transfection into 293H cell line

Order Info

1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.

Specifications

• Antigen: UGT1A6
• Classification: Monoclonal
• Conjugate: Unconjugated
• Formulation: In 1X PBS, pH 7.4
• Gene Accession No.: UGT1A6
• Gene Symbols: UGT1A6
• Immunogen: A synthetic peptide of human UGT1A6
• Regulatory Status: RUO
• Gene ID (Entrez): 54578
• Content And Storage: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
• Isotype: IgG

• Applications: ELISA, Western Blot
• Concentration: 1mg
• Description: UDP glucuronosyltransferase 1 family, polypeptide A6
• Gene: UGT1A6
• Gene Alias: GNT1, HLUGP, HLUGP1, MGC29860, UDPGT, UGT1, UGT1A6S, UGT1F
• Host Species: Rabbit
• Quantity: 1 mg x up to 3 Abs
• Primary or Secondary: Primary
• Target Species: Human
• Form: Liquid