UNC13D, Rabbit, Monoclonal Antibody, Abnova™

Rabbit monoclonal antibody raised against a human UNC13D peptide using ARM Technology.

Supplier:  Abnova Corporation H00201294K

Catalog No. 89-200-718

Includes: Up to three rabbit IgG clones of 1mg each will be delivered to customer.

Description

This gene encodes a protein that is a member of the UNC13 family, containing similar domain structure as other family members but lacking an N-terminal phorbol ester-binding C1 domain present in other Munc13 proteins. The protein appears to play a role in vesicle maturation during exocytosis and is involved in regulation of cytolytic granules secretion. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis type 3, a genetically heterogeneous, rare autosomal recessive disorder. [provided by RefSeq

Library Construction: Nonfusion antibody library from rabbit spleen (ARM Technology)
Expression: Overexpression vector and transfection into 293H cell line

Order Info

1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.

Specifications

• Antigen: UNC13D
• Classification: Monoclonal
• Conjugate: Unconjugated
• Formulation: In 1X PBS, pH 7.4
• Gene Accession No.: UNC13D
• Gene Symbols: UNC13D
• Immunogen: A synthetic peptide of human UNC13D
• Regulatory Status: RUO
• Gene ID (Entrez): 201294
• Content And Storage: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
• Isotype: IgG

• Applications: ELISA, Western Blot
• Concentration: 1mg
• Description: unc-13 homolog D (C. elegans)
• Gene: UNC13D
• Gene Alias: FHL3, HLH3, HPLH3, Munc13-4
• Host Species: Rabbit
• Quantity: 1 mg x up to 3 Abs
• Primary or Secondary: Primary
• Target Species: Human
• Form: Liquid