utrophin, Mouse, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-018-852	50 μL

Catalog No. 89-018-852 Supplier Abnova Corporation Supplier No. H00007402A01

Description

Mouse polyclonal antibody raised against a partial recombinant UTRN.

This gene shares both structural and functional similarities with the dystrophin gene. It contains an actin-binding N-terminus, a triple coiled-coil repeat central region, and a C-terminus that consists of protein-protein interaction motifs which interact with dystroglycan protein components. The protein encoded by this gene is located at the neuromuscular synapse and myotendinous junctions, where it participates in post-synaptic membrane maintenance and acetylcholine receptor clustering. Mouse studies suggest that this gene may serve as a functional substitute for the dystrophin gene and therefore, may serve as a potential therapeutic alternative to muscular dystrophy which is caused by mutations in the dystrophin gene. Alternative splicing of the utrophin gene has been described; however, the full-length nature of these variants has not yet been determined. [provided by RefSeq

Sequence: LEARMQILEDHNKQLESQLHRLRQLLEQPESDSRINGVSPWASPQHSALSYSLDPDASGPQFHQAAGEDLLAPPHDTSTDLTEVMEQIHSTFPSCCPNVPSRPQAM

Specifications

• Antigen: utrophin
• Applications: ELISA, Western Blot
• Classification: Polyclonal
• Conjugate: Unconjugated
• Description: Mouse polyclonal antibody raised against a partial recombinant UTRN.
• Formulation: 50% glycerol
• Gene: UTRN
• Gene Accession No.: NM_007124
• Gene Alias: DMDL/DRP/DRP1/FLJ23678
• Gene Symbols: UTRN
• Host Species: Mouse
• Immunogen: UTRN (NP_009055, 3328 a.a. ∼ 3433 a.a) partial recombinant protein with GST tag.
• Quantity: 50 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 7402
• Target Species: Human
• Content And Storage: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
• Form: Serum