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Description
The GL2 antibody reacts with Vδ 4 T-cell Receptor (TCR)-bearing T cells, which are the predominant γδ TCR-bearing cells in the adult intestinal epithelium (γδ IEL). The frequency of Vδ 4 TCR-bearing γδ IEL differs among inbred strains of mice and may be influenced by haplotypes of the MHC, Tcrg, and/or Tcrd gene complexes. There is evidence that these γδ IEL develop in the absence of thymic influence. T lymphocytes expressing Vδ 4 TCR have also been found in lactating mammary glands, the spleen, and the thymus.
Host Species: Hamster
Clone: GL2
Isotype: IgG2 κ
Species Reactivity: Mouse
Immunogen: G57BL/6 mouse intestinal intra-epithelial lymphocytes
Flow Cytometry
Specifications
Specifications
| Antigen | Vδ 4 TCR |
| Applications | Flow Cytometry |
| Classification | Monoclonal |
| Clone | GL2 |
| Concentration | 0.5mg/mL |
| Conjugate | FITC |
| Formulation | Aqueous buffered solution containing ≤0.09% sodium azide. |
| Host Species | Hamster |
| Immunogen | G57BL/6 mouse intestinal intra-epithelial lymphocytes |
| Purification Method | Affinity Purified |
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For Research Use Only.
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