Vβ 8.3 T-Cell Receptor Hamster anti-Mouse, PE, Clone: 1B3.3, BD

Catalog No.	Quantity
BDB553664	0.1 mg

Catalog No. BDB553664 Supplier BD Biosciences Supplier No. 553664

Description

Hamster Monoclonal Antibody

The 1B3.3 antibody reacts with the Vβ 8.3 T-cell Receptor (TCR), but not the Vβ 8.1 nor Vβ 8.2 TCR, of mice having the b haplotype (e.g., A, AKR, BALB/c, CBA/Ca, CBA/J, C3H/He, C57BL, C58, DBA/1, DBA/2) of the Tcrb gene complex. The Tcrb-V8 subfamily gene loci are deleted in mice having the a (e.g., C57BR, C57L, SJL, SWR) or c (e.g., RIII) haplotype. Vβ 8.3 is one of the restricted TCR β chains expressed by NK-T cells. Staphylococcal enterotoxin B, in association with antigen-presenting cells expressing I-A and/or I-E, stimulates lymphocytes bearing Vβ 8 TCR and selectively eliminates those T cells in vivo. Vβ 8.3 TCR-bearing T-cell clones can be activated by 1B3.3 mAb. This hamster mAb to a mouse leukocyte antigen does not cross-react with rat leukocytes.

Host Species: Hamster
Clone: 1B3.3
Isotype: IgG3, λ1
Species Reactivity: Mouse
Immunogen: Vβ 8.3 TCR-expressing mouse Th1 clone 3.L2

Flow Cytometry

Specifications

• Antigen: Vβ 8.3 T-Cell Receptor
• Applications: Flow Cytometry
• Classification: Monoclonal
• Clone: 1B3.3
• Concentration: 0.2mg/mL
• Conjugate: PE
• Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
• Host Species: Hamster
• Immunogen: Vβ 8.3 TCR-expressing mouse Th1 clone 3.L2
• Purification Method: Affinity Purified
• Quantity: 0.1 mg
• Regulatory Status: RUO
• Research Discipline: Immunology
• Primary or Secondary: Primary
• Target Species: Mouse
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
• Isotype: IgG3

Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov

For Research Use Only.