VASA/DDX4 Human, Unlabeled, Clone: R11-A3, BD

Human Monoclonal Antibody

Supplier:  BD Biosciences 560189

Catalog No. BDB560189

Description

The R11-A3 Fab reacts with a protein of the Asp-Glu-Ala-Asp (DEAD) box (DDX) family that is homologous to the VASA protein of Drosophila. The VASA/DDX4 gene is conserved in invertebrate and vertebrate species, and its expression is germ cell specific. In the human, VASA/DDX4 is expressed in fetal and adult germ cells, both male and female, but not in other fetal and adult tissues. Studies of VASA/DDX4 expression in various types of tumors suggest that expression of VASA/DDX4 is a useful biomarker for germ cell cancers.
The R11-A3 Fab was selected by screening a human Fab phage display library (Hoet et al.) licensed from Dyax Corp (Cambridge, MA) with immobilized recombinant human VASA/DDX4 protein.

Host Species: Human
Clone: R11-A3
Isotype: Ig, λ
Species Reactivity: Mouse

Immunohistochemistry, Western Blotting

Specifications

• Antigen: VASA/DDX4
• Classification: Monoclonal
• Concentration: 0.5mg/mL
• Description: DDX4
• Host Species: Human
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C

• Applications: Western Blot
• Clone: R11-A3
• Conjugate: Unconjugated
• Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
• Immunogen: immunogen is NA for phage display technology
• Quantity: 0.1 mg
• Research Discipline: Cell Biology
• Target Species: Human, Mouse
• Isotype: Ig λ