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VEGF Mouse anti-Human, Unlabeled, Clone: G153-694, BD

Catalog No. BDB555036 Shop All BD Biosciences Products
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BDB555036 0.5 mg
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Catalog No. BDB555036 Supplier BD Biosciences Supplier No. 555036
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Description

Mouse Monoclonal Antibody

Vascular endothelial growth factor (VEGF) is a heparin-binding, dimeric protein related to the PDGF/sis family of growth factors. Major sources of VEGF include pituitary cells, monocytes/macrophages, smooth muscle, and keratinocytes. VEGF is a mitogen for endothelial cells, activates and is chemoattractant for monocytes, enhances blood vessel permeability, and is a pro-coagulant. Human VEGF occurs in several molecular variants arising by alternative splicing of the mRNA. The splice forms of VEGF differ in biological properties. VEGF is a homodimeric heavily glycosylated protein of 46-48kDa (18-25kDa subunits). Glycosylation is not required, however, for biological activity. The subunits are linked by disulphide bonds. Different isoforms of VEGF have different properties in vitro and this may apply also to their in vivo functions.

Immunofluorescence, Immunohistochemistry

TRUSTED_SUSTAINABILITY

Specifications

Antigen VEGF
Applications Immunohistochemistry
Classification Monoclonal
Clone G153-694
Concentration 0.5mg/mL
Conjugate Unconjugated
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species Mouse
Purification Method Affinity Purified
Quantity 0.5 mg
Regulatory Status RUO
Research Discipline Immunology
Primary or Secondary Primary
Target Species Human
Content And Storage Store undiluted at 4°C
Isotype IgG2b κ
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For Research Use Only.

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