Viperin Rabbit anti-Bovine, Canine, Chicken, Equine, Hamster, Human, Mouse, Non-human primate, Porcine, Rabbit, Rat, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA523508
DescriptionViperin is a 43kDa protein which is one of several hundred interferon inducible viral proteins. Elevated expression of viperin is induced by LPS and poly I:C through TLR dependent signaling pathways. Sendai virus mediated viperin expression is induced independently of TLR signaling pathways through RLRs - RIG-I and MAVs (Severa, 2006). Viperin has been shown to play an important role in interferon mediated anti-viral activity in a Hepatitis C virus model system (Helbig, 2011). Viperin is induced in lymphoid cells and dendritic cells (DCs) and highly induced in neutrophils and macrophages during acute LCMV infection in mice (Hinson, ). Viperin functions as a mediator of viral resistance and as a marker for interferon responsiveness making its detection and mechanism of action through specific antibody probes valuable for further studies. Additionally, viperin antibodies provide useful information for analysis of specific cell types responsive to interferon making it valuable for phenotyping studies complementing mechanism of action analysis.
|Portion of amino acids 165-215 of human viperin|
|Bovine, Canine, Chicken, Equine, Hamster, Human, Mouse, Non-human primate, Porcine, Rabbit, Rat|
|Immunohistochemistry (Paraffin), Western Blot|
|PBS with 0.05% BSA and 0.05% sodium azide|
|Q2HJF9, Q8WXG1, Q8CBB9, Q9MZU4, O70600|
|2510004L01Rik, cig33, cig5, vig1, cytomegalovirus-induced gene 5 protein, radical S-adenosyl methionine domain-containing protein 2, viperin, virus inhibitory protein, endoplasmic reticulum-associated, interferon-inducible|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|100072610, 100347276, 100753921, 396752, 428650, 506415, 58185, 609005, 65190, 91543|
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