Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Invitrogen™ WWOX Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA131218
Description
PA1-31218 detects WWOX2 from human, rat, mouse samples.
WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein which contains 2 WW domains and a short-chain dehydrogenase/reductase domain (SRD). The highest normal expression of this gene is detected in hormonally regulated tissues such as testis, ovary, and prostate. This expression pattern and the presence of an SRD domain suggest a role for this gene in steroid metabolism. The encoded protein is more than 90% identical to the mouse protein, which is an essential mediator of tumor necrosis factor-alpha-induced apoptosis, suggesting a similar, important role in apoptosis for the human protein. In addition, there is evidence that this gene behaves as a suppressor of tumor growth. Alternative splicing of this gene generates transcript variants that encode different isoforms.
Specifications
WWOX | |
Polyclonal | |
Unconjugated | |
Wwox | |
5330426P09Rik; 9030416C10Rik; D16S432E; EIEE28; FOR; FRA16D; Fragile site FRA16D oxidoreductase; HHCMA56; PRO0128; SCAR12; SDR41C1; Short chain dehydrogenase/reductase family 41C member 1; short chain dehydrogenase/reductase family 41C, member 1; WOX1; WW domain containing oxidoreductase; WW domain-containing oxidoreductase; WW domain-containing protein WWOX; WW-domain oxidoreductase; Wwox | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
292041, 51741, 80707 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Dot Blot, ELISA | |
0.5 mg/mL | |
Tris glycine with 0.5% BSA, 30% glycerol and 0.02% Sodium azide; pH 7.4-7.9 | |
Q91WL8, Q9NZC7 | |
Wwox | |
Synthetic peptide. | |
100 μg | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |
Safety and Handling
WARNING: Cancer - www.P65Warnings.ca.gov
Product Content Correction
Your input is important to us. Please complete this form to provide feedback related to the content on this product.
Product Title
Spot an opportunity for improvement?Share a Content Correction