XIAP Mouse, Unlabeled, Clone: 28, BD

Mouse Monoclonal Antibody

Catalog Number	Mfr. No.	Quantity
BDB610716	BD Biosciences 610716	50 μg
BDB610717	BD Biosciences 610717	150 μg

Description

Apoptosis is a genetically programmed, selective process of cell death that occurs during normal cell differentiation and development of multicellular organisms. Viruses depend on the biosynthetic machinery of their host cell for the production of progeny and survival. Therefore, many viruses encode proteins that protect the cell from apoptosis. hILP ( h uman I AP- l ike p rotein) is a human homologue of the viral IAP ( I nhibitor of A poptosis P rotein). hILP is a widely expressed cytoplasmic protein of 497 amino acids with three BIR (Baculovirus IAP repeats) domains and a C-terminal RING finger domain. hILP-transfected cells are protected against the apoptotic effects of Sindbis virus infection and ICE (interleukin-1 β; converting enzyme) expression. This product is sold under license from Aegera Therapeutics, Inc.
This antibody is routinely tested by western blot analysis. Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.

Specifications

• Antigen: XIAP
• Concentration: 250μg/mL
• Classification: Monoclonal
• Host Species: Mouse
• Research Discipline: Cell Biology
• Formulation: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
• Isotype: IgG1
• Purification Method: Affinity Purified
• Description: hILP

• Clone: 28
• Applications: Western Blot
• Conjugate: Unconjugated
• Regulatory Status: RUO
• Target Species: Canine, Human, Mouse
• Immunogen: Human hILP/XIAP aa. 268-426
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at -20°C.

For Research Use Only.