XRCC4, Mouse, Polyclonal Antibody, Abnova™

Mouse polyclonal antibody raised against a full-length human XRCC4 protein.

Supplier:  Abnova Corporation H00007518B01

Catalog No. 89-006-459

Description

The protein encoded by this gene functions together with DNA ligase IV and the DNA-dependent protein kinase in the repair of DNA double-strand break by nonhomologous end joining and the completion of V(D)J recombination events. The nonhomologous end-joining pathway is required both for normal development and for suppression of tumors. This gene functionally complements XR-1 Chinese hamster ovary cell mutant, which is impaired in DNA double-strand breaks produced by ionizing radiation and restriction enzymes. Alternative transcription initiation and alternative splicing generates several transcript variants. [provided by RefSeq

Sequence: MERKISRIHLVSEPSITHFLQVSWEKTLESGFVITLTDGHSAWTGTVSESEISQEADDMAMEKGKYVGELRKALLSGAGPADVYTFNFSKESCYFFFEKNLKDVSFRLGSFNLEKVENPAEVIRELICYCLDTIAENQAKNEHLQKENERLLRDWNDVQGRFEKCVSAKEALETDLYKRFILVLNEKKTKIRSLHNKLLNAAQEREKDIKQEGETAICSEMTADRDPVYDESTDEESENQTDLSGLASAAVSKDDSIISSLDVTDIAPSRKRRQRMQRNLGTEPKMAPQENQLQEKENSRPDSSLPETSKKEHISAENMSLETLRNSSPEDLFDEI

Specifications

• Antigen: XRCC4
• Classification: Polyclonal
• Description: Mouse polyclonal antibody raised against a full-length human XRCC4 protein.
• Gene: XRCC4
• Gene Symbols: XRCC4
• Immunogen: XRCC4 (NP_071801.1, 1 a.a. ∼ 336 a.a) full-length human protein.
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Target Species: Human
• Form: Serum

• Applications: Immunofluorescence, Immunohistochemistry (PFA fixed), Western Blot
• Conjugate: Unconjugated
• Formulation: No additive
• Gene Accession No.: NM_022406.1
• Host Species: Mouse
• Quantity: 50 μL
• Whole Molecule: Yes
• Gene ID (Entrez): 7518
• Content And Storage: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.