XRCC4, Mouse, Polyclonal Antibody, Abnova
Mouse polyclonal antibody raised against a full-length human XRCC4 protein.
Manufacturer: Abnova Corporation H00007518B01
The protein encoded by this gene functions together with DNA ligase IV and the DNA-dependent protein kinase in the repair of DNA double-strand break by nonhomologous end joining and the completion of V(D)J recombination events. The nonhomologous end-joining pathway is required both for normal development and for suppression of tumors. This gene functionally complements XR-1 Chinese hamster ovary cell mutant, which is impaired in DNA double-strand breaks produced by ionizing radiation and restriction enzymes. Alternative transcription initiation and alternative splicing generates several transcript variants. [provided by RefSeqSequence: MERKISRIHLVSEPSITHFLQVSWEKTLESGFVITLTDGHSAWTGTVSESEISQEADDMAMEKGKYVGELRKALLSGAGPADVYTFNFSKESCYFFFEKNLKDVSFRLGSFNLEKVENPAEVIRELICYCLDTIAENQAKNEHLQKENERLLRDWNDVQGRFEKCVSAKEALETDLYKRFILVLNEKKTKIRSLHNKLLNAAQEREKDIKQEGETAICSEMTADRDPVYDESTDEESENQTDLSGLASAAVSKDDSIISSLDVTDIAPSRKRRQRMQRNLGTEPKMAPQENQLQEKENSRPDSSLPETSKKEHISAENMSLETLRNSSPEDLFDEI
|XRCC4 (NP_071801.1, 1 a.a. ~ 336 a.a) full-length human protein.|
|Immunofluorescence, Immunohistochemistry (PFA fixed), Western Blot|
|Mouse polyclonal antibody raised against a full-length human XRCC4 protein.|
|Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
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