XRCC4 Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA527107
PA5-27108 targets beta Tubulin 2 in WB applications and shows reactivity with Drosophila and Human samples. The PA5-27108 immunogen is recombit fragment corresponding to a region within amino acids 1 and 356 of Human beta Tubulin 2.The protein encoded by this gene functions together with DNA ligase IV and the DNA-dependent protein kinase in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. The non-homologous end-joining pathway is required both for normal development and for suppression of tumors. This gene functionally complements XR-1 Chinese hamster ovary cell mutant, which is impaired in DNA double-strand breaks produced by ionizing radiation and restriction enzymes. Alternative transcription initiation and alternative splicing generates several transcript variants.
|Recombit fragment corresponding to a region within amino acids 1 and 109 of Human XRCC4|
|Antigen affinity chromatography|
|0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7|
|DNA repair protein XRCC4, X-ray repair cross-complementing protein 4, X-ray repair, complementing defective, repair in Chinese hamster|
|-20° C, Avoid Freeze/Thaw Cycles|
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