XRCC6, Rabbit, Monoclonal Antibody, Abnova™

Rabbit monoclonal antibody raised against a human XRCC6 peptide using ARM Technology.

Supplier:  Abnova Corporation H00002547K

Catalog No. 89-207-998

Includes: Up to three rabbit IgG clones of 1mg each will be delivered to customer.

Description

The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus. [provided by RefSeq

Library Construction: Nonfusion antibody library from rabbit spleen (ARM Technology)
Expression: Overexpression vector and transfection into 293H cell line

Order Info

1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.

Specifications

• Antigen: XRCC6
• Classification: Monoclonal
• Conjugate: Unconjugated
• Formulation: In 1X PBS, pH 7.4
• Gene Accession No.: XRCC6
• Gene Symbols: XRCC6
• Immunogen: A synthetic peptide of human XRCC6
• Regulatory Status: RUO
• Gene ID (Entrez): 2547
• Content And Storage: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
• Isotype: IgG

• Applications: ELISA, Western Blot
• Concentration: 1mg
• Description: X-ray repair complementing defective repair in Chinese hamster cells 6
• Gene: XRCC6
• Gene Alias: CTC75, CTCBF, G22P1, KU70, ML8, TLAA
• Host Species: Rabbit
• Quantity: 1 mg x up to 3 Abs
• Primary or Secondary: Primary
• Target Species: Human
• Form: Liquid