ANTXR1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Catalog No.	Quantity
50-172-9971	150 μL

Catalog No. 50-172-9971 Supplier Proteintech Group Inc Supplier No. 150911AP150UL

Description

Rabbit Polyclonal Antibody

This gene encodes a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants that encode different protein isoforms have been described.

Specifications

• Antigen: ANTXR1
• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 0.27 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene: ANTXR1
• Gene Accession No.: Q0PMD2, Q9CZ52, Q9H6X2
• Gene Alias: anthrax toxin receptor 1, ANTXR1, ATR, TEM8, Tumor endothelial marker 8
• Gene Symbols: Antxr1
• Host Species: Rabbit
• Immunogen: ANTXR1 Fusion Protein Ag4626
• Purification Method: Antigen Affinity Chromatography
• Quantity: 150 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 362393, 69538, 84168
• Target Species: Human, Mouse, Rat
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG