Invitrogen™ AP2 alpha Recombinant Rabbit Monoclonal Antibody (8I8E4)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA538041

Catalog No. PIMA538041

Description

Positive Samples: HeLa, PC-3, NIH/3T3 Immunogen sequence: NADFQPPYFP PPYQPIYPQS QDPYSHVNDP YSLNPLHAQP QPQHPGWPGQ RQSQESGLLH THRGLPHQLS GLDPRRDYRR HEDLLHGPHA LSSGLGDLSI H.

TFAP2A is a sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limbs and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. TFAP2A is the only AP-2 protein required for early morphogenesis of the lens vesicle.

Specifications

• Antigen: AP2 alpha
• Classification: Recombinant Monoclonal
• Concentration: 1.5 mg/mL
• Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P05549, P34056
• Gene Symbols: TFAP2A
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 50-150 of human Activator protein 2 (AP-2/TFAP2A) (P05549).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

• Applications: ELISA, Western Blot
• Clone: 8I8E4
• Conjugate: Unconjugated
• Gene: TFAP2A
• Gene Alias: activating enhancer-binding protein 2 alpha; activating enhancer-binding protein 2-alpha; Activator protein 2; activator protein 2 alpha variant 4; activator protein 2 alpha variant 6; activator protein 2 alpha variant 7; AP2; AP-2; Ap-2 (a); AP-2 transcription factor; AP2alpha; AP-2alpha; AP2-alpha; Ap2tf; BOFS; ERF-1; FLJ51761; OTTHUMP00000214240; OTTHUMP00000214243; Tcfap2a; TFAP2; TFAP2A; transcription factor AP2; transcription factor AP-2 alpha; transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha); transcription factor AP-2, alpha; transcription factor AP-2-alpha; transcription factor AP-2-alpha-like; transcription factor; AP-2
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 21418, 7020
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov