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AP2M1 Mouse anti-Canine, Human, Rat, Clone: OTI 2F11, liquid, TrueMAB™
SDP

Mouse Monoclonal Antibody

Supplier:  OriGene TA503021

Encompass_Preferred

Catalog No. 50-167-3999


May include imposed supplier surcharges.
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Description

Description

The heterotetrameric coat assembly protein complex, also known as the adaptor-related protein complex 2 (AP-2), belongs to the adaptor complexes medium subunits family. The mu 1 subunit of the AP-2 complex (AP2M1) is required for the activity of a vacuolar ATPase, which is responsible for proton pumping occurring in the acidification of endosomes and lysosomes. AP2M1 has also been shown to associate with the HIV-1 protein Nef, suggesting that Nef may use AP-2 complex to enhance the rate of endocytosis of both CD4 and class I MHC. AP2M1 may also play an important role in regulating the intracellular trafficking and function of cytotoxic T-lymphocyte associated (CTLA)-4 protein. At least two isoforms of AP2M1 are known to exist.
Specifications

Specifications

AP2M1
Monoclonal
0.98 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
P84092, Q96CW1
AP2M1
Human recombit protein fragment corresponding to amino acids 97-383 of human AP2M1 produced in E.coli.
100 μL
Primary
Canine, Human, Rat
Antibody
IgG1
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
OTI 2F11
Unconjugated
AP2M1
AP50, CLAPM1, mu2
Mouse
Affinity Chromatography
RUO
116563, 1173, 607139
-20° C, Avoid Freeze/Thaw Cycles
Liquid
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