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AP2M1 Mouse anti-Canine, Human, Rat, Clone: OTI 2F11, liquid, TrueMAB™ Non-distribution product as customer accommodation.

Mouse Monoclonal Antibody

Manufacturer:  OriGeneSupplier Diversity Partner TA503021

Catalog No. 50-167-3999


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Description

Description

The heterotetrameric coat assembly protein complex, also known as the adaptor-related protein complex 2 (AP-2), belongs to the adaptor complexes medium subunits family. The mu 1 subunit of the AP-2 complex (AP2M1) is required for the activity of a vacuolar ATPase, which is responsible for proton pumping occurring in the acidification of endosomes and lysosomes. AP2M1 has also been shown to associate with the HIV-1 protein Nef, suggesting that Nef may use AP-2 complex to enhance the rate of endocytosis of both CD4 and class I MHC. AP2M1 may also play an important role in regulating the intracellular trafficking and function of cytotoxic T-lymphocyte associated (CTLA)-4 protein. At least two isoforms of AP2M1 are known to exist.
Specifications

Specifications

AP2M1
Monoclonal
0.98 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
P84092, Q96CW1
AP50, CLAPM1, mu2
Mouse
IgG1
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
116563, 1173, 607139
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
OTI 2F11
Unconjugated
AP2M1
Liquid
AP2M1
Human recombit protein fragment corresponding to amino acids 97-383 of human AP2M1 produced in E.coli.
Affinity Chromatography
RUO
Antibody
Monoclonal
Canine, Human, Rat
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