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AP2M1 Monoclonal Antibody (OTI2G2), TrueMAB™, OriGene
SDP

Mouse Monoclonal Antibody

Supplier:  OriGene TA503017

Encompass_Preferred

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Catalog No. 50-167-3995


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Description

Description

The heterotetrameric coat assembly protein complex, also known as the adaptor-related protein complex 2 (AP-2), belongs to the adaptor complexes medium subunits family. The mu 1 subunit of the AP-2 complex (AP2M1) is required for the activity of a vacuolar ATPase, which is responsible for proton pumping occurring in the acidification of endosomes and lysosomes. AP2M1 has also been shown to associate with the HIV-1 protein Nef, suggesting that Nef may use AP-2 complex to enhance the rate of endocytosis of both CD4 and class I MHC. AP2M1 may also play an important role in regulating the intracellular trafficking and function of cytotoxic T-lymphocyte associated (CTLA)-4 protein. At least two isoforms of AP2M1 are known to exist.
Specifications

Specifications

AP2M1
Monoclonal
0.98 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
P84091, Q96CW1
AP2M1
Human recombit protein fragment corresponding to amino acids 97-383 of human AP2M1 produced in E.coli.
100 μL
Primary
Human, Mouse
Antibody
IgG2a
Flow Cytometry, Western Blot
OTI2G2
Unconjugated
AP2M1
AP50, CLAPM1, mu2
Mouse
Affinity Chromatography
RUO
1173, 11773
-20° C, Avoid Freeze/Thaw Cycles
Liquid
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