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Invitrogen™ AP3M1 Polyclonal Antibody
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Catalog No. PIPA521162
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100 μg
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PIPA521162 100 μg
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Catalog No. PIPA521162 Supplier Invitrogen™ Supplier No. PA521162
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Rabbit Polyclonal Antibody

A suggested positive control is human brain tissue lysate. PA5-21162 can be used with blocking peptide PEP-1276.

The AP3 complex is a heterotetramer composed of two large adaptins (AP3D1, AP3B1 or AP3B2), a medium adaptin (AP3M1 or AP3M2) and a small adaptin (APS1 or AP3S2). The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. AP3M1 is highly homologous to AP3M2 but is the preferred binding partner to the YQRL motif from the cytosolic domain of TGN38. AP3M1 has also been shown to interact with the HIV-1 virulence protein Nef.
TRUSTED_SUSTAINABILITY

Specifications

Antigen AP3M1
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene Ap3m1
Gene Accession No. P53676, Q9JKC8, Q9Y2T2
Gene Alias 1200013D09Rik; adapter-related protein complex 3 mu-1 subunit; adapter-related protein complex 3 subunit mu-1; adaptor protein complex 3 Mu3A; adaptor related protein complex 3 mu 1 subunit; adaptor related protein complex 3 subunit mu 1; adaptor-related protein complex 3 subunit mu-1; adaptor-related protein complex 3, mu 1 subunit; adaptor-related protein complex AP-3 mu 1 subunit; adaptor-related protein complex AP-3, mu 1 subunit; ap3; AP-3 adapter complex mu3A subunit; AP-3 adaptor complex mu3A subunit; AP-3 complex subunit mu-1; AP-3 complex subunit mu-1-like protein; Ap3m1; C78982; clathrin adaptor complex AP3, mu-3A subunit; clathrin adaptor protein mu3A; clathrin assembly protein assembly protein complex 1 medium chain homolog 1; clathrin assembly protein assembly protein complex 3 mu-1 medium chain; clathrin coat assembly protein AP47 homolog 1; clathrin coat-associated protein AP47 homolog 1; clathrin-associated adaptor protein homolog (p47A); golgi adaptor AP-1 47 kDa protein homolog 1; HA1 47 kDa subunit homolog 1; hypothetical protein; Mu3A-adaptin; mu-adaptin 3A; P47a; R75378; RCJMB04_1h22; Unknown (protein for MGC:137644)
Gene Symbols Ap3m1
Host Species Rabbit
Immunogen A 15 amino acid peptide near the carboxy terminus of human AP3M1.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 171126, 26985, 55946
Target Species Human, Mouse, Rat
Content And Storage Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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