Invitrogen™ AP3M1 Polyclonal Antibody

Catalog No.	Quantity
PIPA587877	100 μL

Catalog No. PIPA587877 Supplier Invitrogen™ Supplier No. PA587877

Description

Rabbit Polyclonal Antibody

Immunogen sequence: SLSFMNPRLL DDVSFHPCIR FKRWESERVL SFIPPDGNFR LISYRVSSQN LVAIPVYVKH SISFKENSSC GRFDITIGPK QNMGKTIEGI TVTVHMPKVV LNMNLTPTQG SYTFDPVTKV LTWDVGKITP QKLPSLKGLV NLQSGAPKPE ENPSLNIQFK IQQLAISGLK VNRLDMYGEK YKPFKGVKYV TKAGKFQVRT; Positive Samples: 22Rv1, Mouse liver, Mouse kidney, Rat spinal cord, Rat liver; Cellular Location: Cytoplasmic side, Cytoplasmic vesicle membrane, Golgi apparatus, Peripheral membrane protein.

The AP3 complex is a heterotetramer composed of two large adaptins (AP3D1, AP3B1 or AP3B2), a medium adaptin (AP3M1 or AP3M2) and a small adaptin (APS1 or AP3S2). The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. AP3M1 is highly homologous to AP3M2 but is the preferred binding partner to the YQRL motif from the cytosolic domain of TGN38. AP3M1 has also been shown to interact with the HIV-1 virulence protein Nef.

Specifications

• Antigen: AP3M1
• Applications: ELISA, Western Blot
• Classification: Polyclonal
• Concentration: 1.78 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene: Ap3m1
• Gene Accession No.: P53676, Q9JKC8, Q9Y2T2
• Gene Alias: 1200013D09Rik; adapter-related protein complex 3 mu-1 subunit; adapter-related protein complex 3 subunit mu-1; adaptor protein complex 3 Mu3A; adaptor related protein complex 3 mu 1 subunit; adaptor related protein complex 3 subunit mu 1; adaptor-related protein complex 3 subunit mu-1; adaptor-related protein complex 3, mu 1 subunit; adaptor-related protein complex AP-3 mu 1 subunit; adaptor-related protein complex AP-3, mu 1 subunit; ap3; AP-3 adapter complex mu3A subunit; AP-3 adaptor complex mu3A subunit; AP-3 complex subunit mu-1; AP-3 complex subunit mu-1-like protein; Ap3m1; C78982; clathrin adaptor complex AP3, mu-3A subunit; clathrin adaptor protein mu3A; clathrin assembly protein assembly protein complex 1 medium chain homolog 1; clathrin assembly protein assembly protein complex 3 mu-1 medium chain; clathrin coat assembly protein AP47 homolog 1; clathrin coat-associated protein AP47 homolog 1; clathrin-associated adaptor protein homolog (p47A); golgi adaptor AP-1 47 kDa protein homolog 1; HA1 47 kDa subunit homolog 1; hypothetical protein; Mu3A-adaptin; mu-adaptin 3A; P47a; R75378; RCJMB04_1h22; Unknown (protein for MGC:137644)
• Gene Symbols: Ap3m1
• Host Species: Rabbit
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 219-418 of human AP3M1 (NP_0362271).
• Purification Method: Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 171126, 26985, 55946
• Target Species: Human, Mouse, Rat
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov