Invitrogen™ AP3M1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5114855

Catalog No. PIPA5114855

Description

Antibody detects endogenous levels of total AP3M1.

The AP3 complex is a heterotetramer composed of two large adaptins (AP3D1, AP3B1 or AP3B2), a medium adaptin (AP3M1 or AP3M2) and a small adaptin (APS1 or AP3S2). The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. AP3M1 is highly homologous to AP3M2 but is the preferred binding partner to the YQRL motif from the cytosolic domain of TGN38. AP3M1 has also been shown to interact with the HIV-1 virulence protein Nef.

Specifications

• Antigen: AP3M1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Ap3m1
• Gene Alias: 1200013D09Rik; adapter-related protein complex 3 mu-1 subunit; adapter-related protein complex 3 subunit mu-1; adaptor protein complex 3 Mu3A; adaptor related protein complex 3 mu 1 subunit; adaptor related protein complex 3 subunit mu 1; adaptor-related protein complex 3 subunit mu-1; adaptor-related protein complex 3, mu 1 subunit; adaptor-related protein complex AP-3 mu 1 subunit; adaptor-related protein complex AP-3, mu 1 subunit; ap3; AP-3 adapter complex mu3A subunit; AP-3 adaptor complex mu3A subunit; AP-3 complex subunit mu-1; AP-3 complex subunit mu-1-like protein; Ap3m1; C78982; clathrin adaptor complex AP3, mu-3A subunit; clathrin adaptor protein mu3A; clathrin assembly protein assembly protein complex 1 medium chain homolog 1; clathrin assembly protein assembly protein complex 3 mu-1 medium chain; clathrin coat assembly protein AP47 homolog 1; clathrin coat-associated protein AP47 homolog 1; clathrin-associated adaptor protein homolog (p47A); golgi adaptor AP-1 47 kDa protein homolog 1; HA1 47 kDa subunit homolog 1; hypothetical protein; Mu3A-adaptin; mu-adaptin 3A; P47a; R75378; RCJMB04_1h22; Unknown (protein for MGC:137644)
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 171126, 26985, 55946
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide
• Gene Accession No.: P53676, Q9JKC8, Q9Y2T2
• Gene Symbols: Ap3m1
• Immunogen: A synthesized peptide derived from human AP3M1(Accession Q9Y2T2), corresponding to amino acid residues K131-F181.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG