Invitrogen™ AP3S2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5120560

Catalog No. PIPA5120560

Description

Positive test controls include: HT-29, Mouse brain, Rat brain. Immunogen sequence: MIQAILVFNN HGKPRLVRFY QRFPEEIQQQ IVRETFHLVL KRDDNICNFL EGGSLIGGSD YKLIYRHYAT LYFVFCVDSS ESELGILDLI QVFVETLDKC FENVCELDLI FHMDKVHYIL QEVVMGGMVL ETNMNEIVAQ IEAQNRLEKS EGGLSAAPAR AVSAVKNINL PEIPRNINIG DLNIKVPNLS QFV.

AP3S2 (Adaptor Related Protein Complex 3 Subunit Sigma 2) is a Protein Coding gene. Among its related pathways are Lysosome. Gene Ontology (GO) annotations related to this gene include protein transporter activity. An important paralog of this gene is AP3S1. Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.

Specifications

• Antigen: AP3S2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: AP3S2
• Gene Alias: [s]3B; adapter-related protein complex 3 sigma-2 subunit; adapter-related protein complex 3 subunit sigma-2; adaptor complex sigma3B; adaptor related protein complex 3 sigma 2 subunit; adaptor related protein complex 3, sigma 2 subunit; adaptor-related protein complex 3 subunit sigma-2; adaptor-related protein complex 3, sigma 2 subunit; adaptor-related protein complex AP-3, sigma 2 subunit; AP-3 complex sigma-3B subunit; AP-3 complex subunit sigma-2; AP-3 complex subunit sigma-3B; AP3S2; AP3S3; clathrin-associated/assembly/adaptor protein, small 4, 22-kD; FLJ35955; sigma 3B; sigma3b; sigma-3B-adaptin; sigma3B-adaptin; Sigma-adaptin 3b
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10239, 11778, 683402
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot, Immunocytochemistry
• Concentration: 2.21 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: P59780, Q8BSZ2
• Gene Symbols: AP3S2
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-193 of human AP3S2 (NP_005820.1).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov