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Invitrogen™ APBA2 Polyclonal Antibody
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Catalog No. PIPA5103599
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Quantity:
100 μL
Catalog No. Quantity
PIPA5103599 100 μL
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Catalog No. PIPA5103599

Supplier: Invitrogen™ PA5103599

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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total APBA2.

APBA2, a member of the X11 protein family, is a phosphotyrosine-binding domain protein and is a neuronal adapter protein that interacts with amyloid precursor protein (APP) and neuritic plaques in the brains of patients with Alzheimer's disease. It stabilizes APP and inhibits production of proteolytic APP fragments including the Abeta peptide that is deposited in the brains of Alzheimer's disease patients. APBA2 is believed to be involved in signal transduction processes and is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. Recent reports suggest that it may also be a candidate gene for autism.
TRUSTED_SUSTAINABILITY

Specifications

Antigen APBA2
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene APBA2
Gene Accession No. O35431, P98084, Q99767
Gene Alias Adapter protein X11beta; amyloid beta (A4) precursor protein-binding family A member 2 (X11-like); amyloid beta (A4) precursor protein-binding, family A, member 2; amyloid beta (A4) precursor protein-binding, family A, member 2 (X11-like); amyloid beta A4 precursor protein-binding family A member 2; amyloid beta precursor protein binding family A member 2; Amyloid-beta A4 precursor protein-binding family A member 2; Apba2; D15S1518E; HsT16821; LIN-10; MGC:14091; Mint 2; Mint2; mint-2; mXllL; Neuronal Munc18-1-interacting protein 2; neuron-specific X11L protein; phosphotyrosine-binding/-interacting domain (PTB)-bearing protein; X11-BETA; X11L; X11-like; X11-like protein; XllL
Gene Symbols APBA2
Host Species Rabbit
Immunogen A synthesized peptide derived from human APBA2(Accession Q99767), corresponding to amino acid residues G253-K303.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11784, 321, 83610
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

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