APBA2 Rabbit anti-Human, Polyclonal, Bethyl Laboratories

Rabbit Polyclonal Antibody

Supplier:  Bethyl Laboratories, Inc A305222A

Catalog No. 50-156-9847

Description

The recommended shelf life for this product is 1 year from date of receipt.

APBA2, a member of the X11 protein family, is a phosphotyrosine-binding domain protein and is a neuronal adapter protein that interacts with amyloid precursor protein (APP) and neuritic plaques in the brains of patients with Alzheimer′s disease. It stabilizes APP and inhibits production of proteolytic APP fragments including the Abeta peptide that is deposited in the brains of Alzheimer′s disease patients. APBA2 is believed to be involved in signal transduction processes and is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. Recent reports suggest that it may also be a candidate gene for autism.

Specifications

• Antigen: APBA2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: APBA2
• Gene Alias: D15S1518E, HsT16821, LIN-10, MGC:14091, MINT2, X11-BETA, X11L; X11-like protein; adapter protein X11beta; amyloid beta (A4) precursor protein-binding, family A, member 2 (X11-like); amyloid beta A4 precursor protein-binding family A member 2; mint-2; neuron-specific X11L protein; neuronal munc18-1-interacting protein 2; phosphotyrosine-binding/-interacting domain (PTB)-bearing protein
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 321
• Content And Storage: 4° C
• Form: Liquid

• Applications: Immunoprecipitation
• Concentration: 1 mg/ml
• Formulation: phosphate, tris citrate with 0.09% sodium azide; pH 7-8
• Gene Accession No.: Q99767
• Gene Symbols: APBA2
• Immunogen: Between 275 and 325
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG