APBB1 Mouse anti-Human, Clone: OTI3H9, lyophilized, TrueMAB™

Catalog No.	Quantity
50-167-0481	100 μg

Catalog No. 50-167-0481 Supplier OriGene Supplier No. CF811159

Description

Mouse Monoclonal Antibody

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

The protein encoded by this gene is a member of the Fe65 protein family. It is an adaptor protein localized in the nucleus. It interacts with the Alzheimer′s disease amyloid precursor protein , transcription factor CP2/LSF/LBP1 and the low-density lipoprotein receptor-related protein. APP functions as a cytosolic anchoring site that can prevent the gene product′s nuclear translocation. This encoded protein could play an important role in the pathogenesis of Alzheimer′s disease. It is thought to regulate transcription. Also it is observed to block cell cycle progression by downregulating thymidylate synthase expression. Multiple alternatively spliced transcript variants have been described for this gene but some of their full length sequence is not known.

Specifications

• Antigen: APBB1
• Applications: Western Blot
• Classification: Monoclonal
• Clone: OTI3H9
• Conjugate: Unconjugated
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene: APBB1
• Gene Accession No.: O00213
• Gene Alias: FE65, MGC:9072, RIR
• Gene Symbols: APBB1
• Host Species: Mouse
• Immunogen: Full length human recombit protein of human APBB1 produced in HEK293T cell.
• Purification Method: Affinity Chromatography
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 322
• Target Species: Human
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Lyophilized
• Isotype: IgG1