APC Mouse anti-Human, Clone: OTI2B8, liquid, TrueMAB™

Catalog No.	Quantity
50-167-9865	100 μL

Catalog No. 50-167-9865 Supplier OriGene Supplier No. TA803655

Description

Mouse Monoclonal Antibody

This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal domit pre-maligt disease that usually progresses to maligcy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product.

Specifications

• Antigen: APC
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Classification: Monoclonal
• Clone: OTI2B8
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene: APC
• Gene Accession No.: P25054
• Gene Alias: BTPS2, DP2, DP2.5, DP3, GS, PPP1R46
• Gene Symbols: APC
• Host Species: Mouse
• Immunogen: Human recombit protein fragment corresponding to amino acids 955-1382 of human APC produced in E.coli.
• Purification Method: Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 324
• Target Species: Human
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1