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Invitrogen™ APC1 Monoclonal Antibody (7G9C7)
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Catalog No. PIMA531620
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100 μL
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Catalog No. Quantity
PIMA531620 100 μL
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Catalog No. PIMA531620 Supplier Invitrogen™ Supplier No. MA531620
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Description

Mouse Monoclonal Antibody

MA5-31620 has been tested in indirect ELISA.

Cell cycle regulated protein ubiquitination and degradation within subcellular domains is thought to be essential for the normal progression of mitosis. APC1, also known as mitotic checkpoint regulator (MCPR), is a highly conserved component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. APC/C is responsible for degrading anaphase inhibitors, mitotic cyclins, and spindle-associated proteins ensuring that events of mitosis take place in proper sequence. The individual APC/C components mRNA and protein levels are expressed at approximately the same levels in most tissues and cell lines, suggesting that they perform their functions as part of a complex.
TRUSTED_SUSTAINABILITY

Specifications

Antigen APC1
Applications ELISA, Flow Cytometry, Western Blot
Classification Monoclonal
Clone 7G9C7
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% sodium azide
Gene ANAPC1
Gene Accession No. Q9H1A4
Gene Alias 2610021O03Rik; AI047775; AI853536; ANAPC1; anaphase promoting complex subunit 1; anaphase-promoting complex 1 (meiotic checkpoint regulator); anaphase-promoting complex subunit 1; APC1; AW547281; Cyclosome subunit 1; Mcpr; meiotic check point regulator; mitotic checkpoint regulator; Testis-specific gene 24 protein; TSG24
Gene Symbols ANAPC1
Host Species Mouse
Immunogen Purified recombinant fragment of human ANAPC1 (AA: 12-155) expressed in E. coli.
Purification Method Protein G
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 64682
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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